Article
DNA profiling in a genetically isolated population using three hypervariable DNA markers.
Human heredity - 1 Jan 1992
Sajantila A, Makkonen K, Ehnholm C, Peltonen L
Abstract excerpt
We determined the allele frequencies for three hypervariable DNA loci D2S44, D1S7 and D7S21 using the probes YNH24, MS1 and MS31 in the genetically isolated Finnish population. The allelic length ranges were 1.7- < 6.0 kb for YNH24, 1.7- < 18.0 kb for MS1 and 3.2- < 12.0 kb for MS31. High heterozygosity rates (0.94-0.96) were detected for all three probes. In 48 mother-child pairs no mutations were found using...
Topics
- Adult
- Alleles
- Child
- DNA
- DNA Fingerprinting
- DNA Probes
- Female
- Finland
- Gene Frequency
- Genetic Markers
- Humans
- Male
- Mutation
