Article
Molecular and genetic characterization and physical mapping of 11 new markers detecting multiallele restriction fragment length polymorphisms on the short arm of human chromosome 3.
Human genetics - 1 Jan 2000
Latif F, Modi W S, Duh F M, Schmidt L, Li H, Geil L, Orcutt M L, Heppell-Parton A, Rabbitts P H, Linehan W M
Abstract excerpt
Genetic markers with high degrees of polymorphisms are of vital importance in the construction of high resolution (2-4 cM) linkage maps of human chromosomes as specified in the short-term goals of the Human Genome Initiative. In this paper, we report on molecular and genetic characterization and...
Topics
- Alleles
- Base Sequence
- Chromosomes, Human, Pair 3
- Female
- Genetic Markers
- Humans
- In Situ Hybridization, Fluorescence
- Male
- Molecular Sequence Data
- Pedigree
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length