Article
[Current molecular prognostic factors in breast carcinoma].
Schweizerische medizinische Wochenschrift - 3 Oct 1992
Fey M F, Andres A C, Castiglione-Gertsch M
Abstract excerpt
In breast cancer the tumor stage, axillary lymph node metastases and hormone receptors are well established prognostic factors. Nevertheless, additional prognostic factors are still desirable. Recently, attention has focussed on molecular markers, in particular mutated genes involved in the pathogenesis of breast carcinoma. The first such marker to be tested for its clinical relevance has been the c-erbB-2...
Topics
- Biomarkers, Tumor
- Breast Neoplasms
- Female
- Gene Amplification
- Gene Expression Regulation, Neoplastic
- Humans
- Mutation
- Proto-Oncogene Proteins
- Proto-Oncogenes
- Receptor, ErbB-2
- Receptors, Estrogen