Article
Prognostic and predictive indicators in operable breast cancer.
Clinical breast cancer - 1 Feb 2003
Morabito Alessandro, Magnani Elena, Gion Massimo, Sarmiento Roberta, Capaccetti Barbara, Longo Raffaele, Gattuso Domenico, Gasparini Giampietro
Abstract excerpt
Because of its biological heterogeneity and wide spectrum of responsiveness to different treatments, breast cancer is a complex disease of difficult clinical management. Over the past several years, knowledge of the molecular mechanisms regulating normal and aberrant cell growth leading to cancer has been enhanced. These advances have enabled the identification of an increasing number of surrogate biomarkers,...
Topics
- Breast Neoplasms
- Carcinoma, Medullary
- Disease-Free Survival
- Female
- Genes, erbB-1
- Genes, p53
- Humans
- Ki-67 Antigen
- Lymphatic Metastasis
- Mutation
- Neoplasm Invasiveness
- Neovascularization, Pathologic
- Prognosis
- Receptors, Estrogen
