HLA-DQA1 and MLC among HLA (generic)-identical unrelated individuals.

doi:10.1111/j.1399-0039.1992.tb01934.x

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Article

HLA-DQA1 and MLC among HLA (generic)-identical unrelated individuals.

Tissue antigens - 1 Apr 1992

Yunis I, Salazar M, Alosco S M, Gomez N, Yunis E J

Abstract excerpt

We modified a previously published PCR-RFLP for DQA1 typing (1) and examined the predictive value of HLA-DQA1 in mixed lymphocyte cultures (MLC) among matched (HLA generic types) pairs of unrelated individuals. There were 61/102 (60%) pairs with positive MLC, one-third of which could be predicted...

Topics

Alleles
Base Sequence
Genes, MHC Class II
HLA-DQ Antigens
HLA-DQ alpha-Chains
Haplotypes
Humans
Lymphocyte Culture Test, Mixed
Molecular Sequence Data
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
Predictive Value of Tests

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