Article
HLA-DQA1 and MLC among HLA (generic)-identical unrelated individuals.
Tissue antigens - 1 Apr 1992
Yunis I, Salazar M, Alosco S M, Gomez N, Yunis E J
Abstract excerpt
We modified a previously published PCR-RFLP for DQA1 typing (1) and examined the predictive value of HLA-DQA1 in mixed lymphocyte cultures (MLC) among matched (HLA generic types) pairs of unrelated individuals. There were 61/102 (60%) pairs with positive MLC, one-third of which could be predicted by DQA1* typing alone. DQA1 matching and MLC reactions were classified into 3 groups: 1) DQA1 mismatches showing...
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