Article
Allotype distribution of human T cell receptor beta and gamma chain genes in Caucasians, Asians and Australian aborigines: relevance to chronic hepatitis B.
Human genetics - 1 Apr 1992
Soeharso P, Summers K M, Cooksley W G
Abstract excerpt
RFLPs of TCR beta and gamma genes have been analyzed in chronic HBV carriers of three different ethnic populations to determine if there is an association of TCR allotypes with the development of chronic hepatitis B. The RFLPs of TCR beta and gamma genes were defined respectively by BglII and PvuII genomic fragments on Southern blots. These methods allow allotype assignment. The distribution of TCR beta alleles...
Topics
- Alleles
- Asian People
- Blotting, Southern
- Carrier State
- Chronic Disease
- Hepatitis B
- Humans
- Polymorphism, Restriction Fragment Length
- Racial Groups
- Receptors, Antigen, T-Cell, alpha-beta
- Receptors, Antigen, T-Cell, gamma-delta