Article
Clonal differences within M-types of the group A Streptococcus revealed by pulsed field gel electrophoresis.
FEMS microbiology letters - 1 Feb 1992
Single L A, Martin D R
Abstract excerpt
Digestion of chromosomal DNA with the rare cutting restriction enzyme SfiI in association with pulsed field gel electrophoresis was used to observe restriction fragment length polymorphisms (RFLP) among isolates of group A Streptococcus. Streptococci examined included isolates belonging to the same M-type (epidemiologically related and unrelated), and isolates from other M-types. RFLP patterns were quite distinct...
Topics
- DNA, Bacterial
- Electrophoresis, Gel, Pulsed-Field
- Genetic Variation
- Polymorphism, Restriction Fragment Length
- Serotyping
- Streptococcus pyogenes
