Article
[Role of fructose-1-phosphate kinase in expression of PEP-synthase in Escherichia coli K-12].
Genetika - 1 Aug 1992
Molchanova M L, Erdagaeva R S, Grigorenko Iu A, Bol'shakova T N, Gershanovich V N
Abstract excerpt
Mutational damage of the fruK gene coding for fructose-1-phosphate kinase leads to 2-6-fold (depending on the strain) decrease in FEP synthase activity in Escherichia coli. The fruK mutants were unable to utilize lactate as well as fructose and fructose-1-phosphate, acquiring, in addition, sensitivity to mannose in their growth medium. Reversions back to FruK+ phenotype or introduction of an intact fruK allele...
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