Article
Direct detection of Epstein-Barr virus in peripheral blood and comparison of Epstein-Barr virus genotypes present in direct specimens and lymphoblastoid cell lines established from nasopharyngeal carcinoma patients and healthy carriers in Hong Kong.
International journal of cancer - 9 Sept 1992
Lung M L, Lam W P, Chan K H, Li S, Sham J, Choy D
Abstract excerpt
By means of a PCR assay, EBV was demonstrated directly in peripheral blood of previously infected individuals. The virus was detected in approximately 80% of specimens from EBV-seropositive individuals, but not in cord-blood lymphocytes by this method. When virus present in peripheral blood was compared to that observed directly in NPC biopsies or throat washings, it was distinct from that seen in biopsies in...
Topics
- Blotting, Southern
- Carrier State
- Cell Line
- DNA, Viral
- Genotype
- Herpesvirus 4, Human
- Hong Kong
- Humans
- Lymphocytes
- Nasopharyngeal Neoplasms