Article
Molecular and immunophenotypic characterization of AIDS-associated, Epstein-Barr virus-negative, polyclonal lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Mar 1992
Shiramizu B, Herndier B, Meeker T, Kaplan L, McGrath M
Abstract excerpt
PURPOSE: A molecular analysis of non-Hodgkin's lymphomas (NHLs) from patients with AIDS was undertaken to determine the prevalence and immunophenotype of polyclonal B-cell lymphoma. MATERIALS AND METHODS: DNA was extracted from 40 diagnostic biopsy specimens obtained from patients seen at University of California, San Francisco (UCSF) between 1986 and 1990. Clonality, infection with Epstein-Barr virus (EBV), and...
Topics
- Blotting, Southern
- DNA, Neoplasm
- Gene Rearrangement
- Genes, Immunoglobulin
- Genes, myc
- Genotype
- Herpesvirus 4, Human
- Humans
- Immunophenotyping
- Lymphoma, AIDS-Related
