Article
The interaction between Sillence type and BMD in osteogenesis imperfecta.
Calcified tissue international - 1 Nov 2003
Kok D J, Uiterwaal C S P M, Van Dongen A J, Kramer P P G, Pruijs H E H, Engelbert R H H, Verbout A J, Schweitzer D H, Sakkers R J B
Abstract excerpt
Clinical studies with bisphosphonates in children with osteogenesis imperfecta (OI) show an increase in BMD and a decrease in fracture rate. Bone strength in children with OI is not only influenced by changes in BMD but also by changes in collagen I structure of the organic bone matrix. Therefore...
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