Article
Can drug resistance mutations influence the measurement of plasma HIV-RNA by different viral load techniques?
AIDS patient care and STDs - 1 Jul 2003
Poveda Eva, de Mendoza Carmen, Cuesta Marta, Toro Carlos, Rodés Berta, Soriano Vincent
Abstract excerpt
Guidelines for the use of antiretroviral agents consider that viral load values may differ using the branched DNA (bDNA) and polymerase chain reaction (PCR) methods. Whereas the most commonly used PCR assay (Amplicor v1.5, Roche) targets HIV gag sequences, the bDNA (Quantiplex v3.0, Bayer) is based on the recognition of HIV pol sequences. The possibility that accumulation of drug-resistance mutations at the...
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