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Article

Bone morphogenetic protein-4 gene polymorphism and early marginal bone loss around endosseous implants.

The International journal of oral & maxillofacial implants - 1 Jan 2000

Shimpuku Hitomi, Nosaka Yasuhiro, Kawamura Tatsuya, Tachi Yoichi, Shinohara Mitsuko, Ohura Kiyoshi

Abstract excerpt

PURPOSE: At stage II surgery during dental implant treatment, early marginal bone loss around the implant occasionally occurs despite a lack of apparent causal events, and the etiology of this bone loss is unclear. This study was designed to investigate whether the bone morphogenetic protein-4 (BMP-4) genetic polymorphism is associated with early marginal bone loss around implants. MATERIALS AND METHODS: The...

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PMID: 12939000

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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