Article
Haplotyping as perfect phylogeny: a direct approach.
Journal of computational biology : a journal of computational molecular cell biology - 1 Jan 2003
Bafna Vineet, Gusfield Dan, Lancia Giuseppe, Yooseph Shibu
Abstract excerpt
A full haplotype map of the human genome will prove extremely valuable as it will be used in large-scale screens of populations to associate specific haplotypes with specific complex genetic-influenced diseases. A haplotype map project has been announced by NIH. The biological key to that project is the surprising fact that some human genomic DNA can be partitioned into long blocks where genetic recombination has...
Topics
- Algorithms
- Data Interpretation, Statistical
- Genetic Predisposition to Disease
- Haplotypes
- Phylogeny
