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Article

Chemoprevention of Skin Cancer in Xeroderma Pigmentosum

1 Nov 1992

Abstract excerpt

Xeroderma pigmentosum is a rare recessive disease with sun sensitivity, increased freckling and defective DNA repair. Xeroderma pigmentosum patients have more than a 1000-fold increased risk of developing skin cancer including basal cell carcinoma, squamous cell carcinoma and melanoma. We studied chemoprevention of new skin cancers with oral retinoids in xeroderma pigmentosum patients who had multiple skin...

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PMID: 1293159
DOI: 10.1111/j.1346-8138.1992.tb03766.x

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