Article
[Sporadic and hereditary colorectal cancer. Pathogenetically different with different therapeutic indications].
Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen - 1 Aug 2003
Weitz J, Knaebel H-P, Büchler M W
Abstract excerpt
In recent years, there have been major advances regarding the understanding of the pathogenesis of sporadic and hereditary colorectal cancer on the basis of molecular research. The clinical implications of this knowledge differ for the sporadic and hereditary forms. In sporadic colorectal cancer, gene mutations occur in colorectal cells but not as germline mutations. Even though molecular data currently do not...
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