Article
[Hereditary colorectal carcinogenesis].
Pathologie (Heidelberg, Germany) - 1 Sept 2023
Bläker Hendrik
Abstract excerpt
Hereditary cancer is characterized by the development of certain cancer types in combination with pathogenic germline mutations in genes known to predispose to these cancer types. Familial cancer differs from hereditary cancer in that no predisposing germline mutation is detected in affected families. However, familial cancer may have a genetic background of as yet unknown origin. Colorectal cancer is unique...
Topics
- Humans
- Adenomatous Polyposis Coli
- Colorectal Neoplasms
- Genetic Predisposition to Disease
- Peutz-Jeghers Syndrome
- Cell Transformation, Neoplastic
