Article
Nasopharyngeal/nasal type T/NK lymphomas: analysis of 14 cases and review of the literature.
Tumori - 1 Jan 2000
García-Cosío Mónica, Santón Almudena, Méndez M Carmen, Rivas Carmen, Martín Carmen, Bellas Carmen
Abstract excerpt
AIMS AND BACKGROUND: Lymphoid malignancies expressing CD56 are rare and most occur in the nasal or nasopharyngeal region. They derive from natural killer cells or from a small subset of T cells that have granular cytoplasm containing molecules that mediate cytotoxic activity: TIA-1, granzyme B and perforin. Both types are closely associated with Epstein-Barr virus. METHODS: We report the pathologic,...
Topics
- Adult
- Aged
- Cell Lineage
- DNA, Viral
- Epstein-Barr Virus Infections
- Female
- Gene Rearrangement
- Genotype
- Granulocyte Colony-Stimulating Factor
- Herpesvirus 4, Human
- Humans
- Immunoenzyme Techniques
- Immunophenotyping
- In Situ Hybridization
