Article
Tissue-engineered cartilage and bone using stem cells from human infrapatellar fat pads.
The Journal of bone and joint surgery. British volume - 1 Jul 2003
Dragoo J L, Samimi B, Zhu M, Hame S L, Thomas B J, Lieberman J R, Hedrick M H, Benhaim P
Abstract excerpt
Multipotential processed lipoaspirate (PLA) cells extracted from five human infrapatellar fat pads and embedded into fibrin glue nodules, were induced into the chondrogenic phenotype using chondrogenic media. The remaining cells were placed in osteogenic media and were transfected with an adenovirus carrying the cDNA for bone morphogenetic protein-2 (BMP-2). We evaluated the tissue-engineered cartilage and bone...
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