Article
Molecular genetic analysis for the Ae1 and A3 alleles.
Transfusion - 1 Aug 2003
Sun Chien-Feng, Yu Lung-Chih, Chen Ing-Ping, Chou Ding-Lun, Twu Yuh-Ching, Wang Wei-Ting, Lin Marie
Abstract excerpt
BACKGROUND: In addition to the common ABO phenotypes, numerous phenotypes with a weak expression of the A or B antigens on RBCs have been found. This study describes the molecular genetic analysis of the Ael and the A3 phenotypes. STUDY DESIGN AND METHODS: The seven-exon regions of the ABO genes of Ael and A3B individuals were amplified by PCR and cloned, and the sequences of the exons and their adjacent splice...
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