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Remission of Rheumatoid Arthritis During Pregnancy and Maternal‐Fetal Class II Alloantigen Disparity

12 Oct 1992

Abstract excerpt

Rheumatoid arthritis (RA) is an autoimmune disorder known to be associated with specific class II genes. Although it has been known since 1938 that the majority of women with RA experience disease improvement or remission during pregnancy, the reasons remain unknown. Pregnancy represents an immunologic challenge and maternal immune recognition of the semi-allogeneic fetus occurs as part of normal pregnancy. We...

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PMID: 1285885
DOI: 10.1111/j.1600-0897.1992.tb00798.x

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