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Article

Lewis type 1 antigen synthase (beta3Gal-T5) is transcriptionally regulated by homeoproteins.

The Journal of biological chemistry - 19 Sept 2003

Isshiki Soichiro, Kudo Takashi, Nishihara Shoko, Ikehara Yuzuru, Togayachi Akira, Furuya Akiko, Shitara Kenya, Kubota Tetsuro, Watanabe Masahiko, Kitajima Masaki, Narimatsu Hisashi

Abstract excerpt

The type 1 carbohydrate chain, Galbeta1-3GlcNAc, is synthesized by UDP-galactose:beta-N-acetylglucosamine beta1,3-galactosyltransferase (beta3Gal-T). Among six beta3Gal-Ts cloned to date, beta3Gal-T5 is an essential enzyme for the synthesis of type 1 chain in epithelium of digestive tracts or pancreatic tissue. It forms the type 1 structure on glycoproteins produced from such tissues. In the present study, we...

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PMID: 12855703
DOI: 10.1074/jbc.M302681200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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