Growth factors, growth factor response elements, and the cardiac phenotype.

doi:10.1007/978-3-642-72477-0_4

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Article

Growth factors, growth factor response elements, and the cardiac phenotype.

Basic research in cardiology - 1 Jan 1992

Schneider M D, McLellan W R, Black F M, Parker T G

Abstract excerpt

Fibroblast growth factors (FGF) and type beta-1 transforming growth factor (TGF beta 1) are pleiotropic regulatory peptides which are expressed in myocardium in a precise developmental and spatial program and are up-regulated, in the adult heart, by ischemia or a hemodynamic burden. The accumulation of trophic factors after aortic banding supports the hypothesis that autocrine or paracrine pathways might function...

Topics

Actins
Animals
Base Sequence
DNA-Binding Proteins
Fibroblast Growth Factor 1
Fibroblast Growth Factor 2
Gene Expression Regulation
Growth Substances
Heart
Molecular Sequence Data
Muscles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Myocardium

Nuclear Proteins

Phenotype

Promoter Regions, Genetic

Serum Response Factor

Source

Open in PubMed

Identifiers

PMID: 1284369
DOI: 10.1007/978-3-642-72477-0_4

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1284369-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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