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Article

A novel CFTR mutation, 4035delA, detected by non-radioactive SSCP analysis.

Human genetics - 1 Nov 1992

Reiss J, Lenz U, Rininsland F, Ballhausen P, Drews D, Posselt H G

Abstract excerpt

German cystic fibrosis patients were screened for mutations in exon 21 of the cystic fibrosis transmembrane conductance regulator gene by a non-radioactive variation of the single-strand conformation polymorphism technique. Asymmetric polymerase chain reaction amplification was used to produce single strands of exon-containing genomic sequences that were analyzed on polyacrylamide gels subsequently stained with...

Topics

Base Sequence
Child
Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
DNA, Single-Stranded
Exons
Humans
Male
Membrane Proteins
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Sequence Deletion

Source

Identifiers

PMID: 1283151
DOI: 10.1007/BF00220085

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1283151-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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A novel CFTR mutation, 4035delA, detected by non-radioactive SSCP analysis.PMID 1283151Read ↗

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