[The effect of insulin therapy on the level of natural killer cells of different immunological phenotypes (CD16+, CD56+ and CD57+) in the blood of patients with diabetes mellitus type I].

Article

[The effect of insulin therapy on the level of natural killer cells of different immunological phenotypes (CD16+, CD56+ and CD57+) in the blood of patients with diabetes mellitus type I].

Likars'ka sprava - 1 Aug 1992

Gruzov M A, Shliakhovenko V S, Zak K P, Efimov A S, Kalinovskiĭ A K, Mikhaĭlovsksia E V, Sliusarenko N S

Abstract excerpt

Flow cytometry with monoclonal antibody Leu-7 (CD57), Leu-11 (CD56) and Leu-19 (CD56) were used to study the content of different subpopulations of natural killer cells (NK-cells) in the blood of type I diabetes mellitus patients before and after insulin treatment and in healthy people. After a course of insulin therapy most patients showed restoration of the total cell number with antigens on their surface...

Topics

Antigens, CD
Antigens, Differentiation, T-Lymphocyte
CD56 Antigen
CD57 Antigens
Diabetes Mellitus, Type 1
Flow Cytometry
Humans
Insulin
Insulin, Long-Acting
Killer Cells, Natural

Leukocyte Count

Phenotype

Receptors, IgG

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