Article
Prepattern genes and signaling molecules regulate stripe expression to specify Drosophila flight muscle attachment sites.
Mechanisms of development - 1 May 2003
Ghazi Arjumand, Paul Litty, VijayRaghavan K
Abstract excerpt
In Drosophila, muscles attach to epidermal tendon cells specified by the gene stripe (sr). Flight muscle attachment sites are prefigured on the wing imaginal disc by sr expression in discrete domains. We describe the mechanisms underlying the specification of these domains of sr expression. We show that the concerted activities of the wingless (wg), decapentaplegic (dpp) and Notch (N) signaling pathways, and the...
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