Article
Mannose binding lectin gene polymorphism in patients with type I diabetes.
Human immunology - 1 Jun 2003
Tsutsumi Akito, Ikegami Hiroshi, Takahashi Reiko, Murata Hideyuki, Goto Daisuke, Matsumoto Isao, Fujisawa Tomomi, Sumida Takayuki
Abstract excerpt
Our purpose was to investigate a possible relationship between occurrence of type I diabetes and polymorphism of the mannose binding lectin gene. Polymorphism of codon 54 of the mannose binding lectin (MBL) gene, whose presence of the minority allele leads to significant reduction of serum MBL concentration, was investigated in 128 Japanese patients with type I diabetes and 78 healthy volunteers by restriction...
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