Article
Identification of MeCP2 mutations in a series of females with autistic disorder.
Pediatric neurology - 1 Mar 2003
Carney Regina M, Wolpert Chantelle M, Ravan Sarah A, Shahbazian Mona, Ashley-Koch Allison, Cuccaro Michael L, Vance Jeffery M, Pericak-Vance Margaret A
Abstract excerpt
Rett disorder and autistic disorder are both pervasive developmental disorders. Recent studies indicate that at least 80% of Rett Disorder cases are caused by mutations in the methyl-CpG-binding protein 2 (MeCP2) gene. Since there is some phenotypic overlap between autistic disorder and Rett disorder, we analyzed 69 females clinically diagnosed with autistic disorder for the presence of mutations in the MeCP2...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.