Article
Subclinical skeletal muscle abnormalities in patients with hypertrophic cardiomyopathy and their relation to clinical characteristics.
International journal of cardiology - 1 Jun 2003
Anastasakis Aris, Karandreas Nikos, Stathis Pantelis, Rigopoulos Angelos, Theopistou Artemisia, Sepp Robert, Elliott Perry M, Panagiotakos Demosthenes B, Stefanadis Christodoulos, Toutouzas Pavlos
Abstract excerpt
BACKGROUND: Some mutations of cardiac sarcomeric proteins causing hypertrophic cardiomyopathy (beta-myosin heavy chain) are associated with skeletal muscle fiber dysfunction, while subclinical skeletal myopathy can be diagnosed by electromyography (EMG) in a substantial proportion of hypertrophic cardiomyopathy patients. METHODS: In 49 consecutive, unrelated patients with hypertrophic cardiomyopathy, conventional...
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