Article
Allele-specific differential expression of a common adiponectin gene polymorphism related to obesity.
Journal of molecular medicine (Berlin, Germany) - 1 Jul 2003
Yang Wei-Shiung, Tsou Pei-Ling, Lee Wei-Jei, Tseng Da-Lun, Chen Chi-Ling, Peng Chi-Chung, Lee Kuan-Ching, Chen Mei-Ju, Huang Chang-Jen, Tai Tong-Yuan, Chuang Lee-Ming
Abstract excerpt
Adiponectin gene polymorphisms have recently been reported to be associated with obesity, insulin sensitivity, and the risk of type 2 diabetes. We examined a T94G polymorphism of the adiponectin gene in 245 ostensibly normal nondiabetic subjects. The G allele frequency was lower among subjects with higher BMI (> or =27) than in those with lower BMI. BMI was inversely correlated with the dose of G allele....
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