Article
Identification of metastasis-associated proteins by proteomic analysis and functional exploration of interleukin-18 in metastasis.
Proteomics - 1 May 2003
Jiang Daifeng, Ying Wantao, Lu Yinglin, Wan Jinghong, Zhai Yun, Liu Wanli, Zhu Yunping, Qiu Zongyin, Qian Xiaohong, He Fuchu
Abstract excerpt
Very little is currently known about mechanisms underlying cancer metastasis. In the present study, metastasis-associated proteomes were separated and identified by comparative proteomic analysis, and the metastasis-related function of candidate protein interleukin-18 (IL-18) was further elucidated. First, a pair of highly and poorly metastatic sublines (termed PLA801D and PLA801C, respectively), originating from...
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