Article
Mutation prevention concentration of ceftriaxone, meropenem, imipenem, and ertapenem against three strains of Streptococcus pneumoniae.
Diagnostic microbiology and infectious disease - 1 Apr 2003
Hovde Laurie B, Rotschafer Sarah E, Ibrahim Khalid H, Gunderson Brent, Hermsen Elizabeth D, Rotschafer John C
Abstract excerpt
This investigation tested the mutation prevention concentration (MPC) concept using imipenem, meropenem, ceftriaxone, and ertapenem against three strains of Streptococcus pneumoniae (PCN MIC = 0.012, 1, 8 mg/L, respectively). MIC, MBC, and MPC values for each of the beta-lactams did not differ by more than one tube dilution. While an interesting concept, MPC may not apply to antimicrobials that do not utilize a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.