Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PDS is a new susceptibility gene to autoimmune thyroid diseases: association and linkage study.

The Journal of clinical endocrinology and metabolism - 1 May 2003

Hadj Kacem Hassen, Rebai Ahmed, Kaffel Noureddine, Masmoudi Saber, Abid Mohamed, Ayadi Hammadi

Abstract excerpt

Autoimmune thyroid disease (AITD), including Graves' disease (GD), Hashimoto thyroiditis (HT), and primary idiopathic myxedema, is caused by multiple genetic and environmental factors. Genes involved in immune response and/or thyroid physiology appear to influence susceptibility to disease. The PDS gene (7q31), responsible for Pendred syndrome (congenital sensorineural hearing loss and goiter), encodes a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmune Diseases
Share to Carrier Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Linkage

Share to Lod Score

Share to Membrane Transport Proteins

Share to Models, Biological

Share to Sulfate Transporters

Share to Thyroid Diseases

Source

Identifiers

PMID: 12727986
DOI: 10.1210/jc.2002-021460

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PDS is a new susceptibility gene to autoimmune thyroid diseases: association and linkage study.PMID 12727986Read ↗

Molecular analysis of the PDS gene in Pendred syndrome.Semantic proximity Read ↗

Functional differences of the PDS gene product are associated with phenotypic variation in patients with Pendred syndrome and non-syndromic hearing loss (DFNB4).Semantic proximity Read ↗

Pendred syndrome.Semantic proximity Read ↗

Pendred syndrome is caused by mutations in a putative sulphate transporter gene (PDS).Semantic proximity Read ↗

[Pendred syndrome among patients with hypothyroidism: genetic diagnosis, phenotypic variability and occurrence of phenocopies].Semantic proximity Read ↗

Searching for the autoimmune thyroid disease susceptibility genes: from gene mapping to gene function.Semantic proximity Read ↗

Clinical and molecular characteristics of Pendred syndrome.Semantic proximity Read ↗

Pendred's Syndrome: Identification of the Genetic Defect a Century After Its RecognitionSemantic proximity Read ↗

[Pendrin: physiology, molecular biology and clinical importance].Semantic proximity Read ↗

Analysis of clinical characteristics of thyroid phenotype in Pendred syndrome based on multiple databases.Semantic proximity Read ↗

Pendrin, the Protein Encoded by the Pendred Syndrome Gene (PDS), Is an Apical Porter of Iodide in the Thyroid and Is Regulated by Thyroglobulin in FRTL-5 CellsSemantic proximity Read ↗

Iodide handling disorders (NIS, TPO, TG, IYD).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.