Article
Endothelial nitric oxide synthase gene polymorphism in the Indian and Mestizo populations of Mexico.
Human biology - 1 Feb 2003
Rosas-Vargas Haydeé, Flores-Segura Adrián, Guizada-Claure Boris, Vargas-Alarcón Gilberto, Granados Julio, Salamanca Fabio, Coral-Vázquez Ramón
Abstract excerpt
Endothelium-derived nitric oxide (NO) is an important factor in vasodilation synthesized by endothelial nitric oxide synthase (eNOS). A polymorphism (894 G to T) in exon 7 of the eNOS gene causes the conversion of Glu to Asp in position 298. The Glu298Asp polymorphism has been extensively associated with cardiovascular disease. We determined the Glu298Asp polymorphism frequency in healthy Mexican Mestizo,...
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