Article
The mature male sheep: a model to study the effects of nutrition on the reproductive axis.
Reproduction (Cambridge, England). Supplement - 1 Jan 2002
Blache D, Adam C L, Martin G B
Abstract excerpt
We have been using mature male sheep to study the ways in which nutrition affects reproduction, with a focus on the brain-pituitary axis and, in particular, GnRH activity. The sheep model has four major advantages for such studies. Firstly, sheep are large enough to support long periods of frequent serial sampling of peripheral blood, hypophyseal portal blood and cerebrospinal fluid from the cerebral ventricles....
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