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Article

The effects of insertional mutations in comQ, comP, srfA, spo0H, spo0A and abrB genes on bacilysin biosynthesis in Bacillus subtilis.

Biochimica et biophysica acta - 15 Apr 2003

Karataş Ayten Yazgan, Cetin Seçil, Ozcengiz Gülay

Abstract excerpt

In Bacillus subtilis, two extracellular signaling peptides, ComX pheromone and CSF (competence and sporulation factor), stimulate the development of genetic competence and surfaction biosynthesis in response to high cell density (quorum sensing) by regulating the activity of transcription factor ComA. We recently showed that biosynthesis of dipeptide antibiotic bacilysin is linked to ComA and PhrC(CSF) in a...

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PMID: 12697329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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The effects of insertional mutations in comQ, comP, srfA, spo0H, spo0A and abrB genes on bacilysin biosynthesis in Bacillus subtilis.PMID 12697329Read ↗

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The primary role of comA in establishment of the competent state in Bacillus subtilis is to activate expression of srfA.Semantic proximity Read ↗

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