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Article

Gene expression profile of AIDS-related Kaposi's sarcoma

18 Mar 2003

Abstract excerpt

BACKGROUND: Kaposi's Sarcoma (KS) is a proliferation of aberrant vascular structures lined by spindle cells, and is caused by a gammaherpes virus (HHV8/KSHV). Its course is aggravated by co-infection with HIV-1, where the timing of infection with HIV-1 and HHV8 is important for the clinical outcome. METHODS: In order to better understand the pathogenesis of KS, we have analysed tissue from two AIDS-KS lesions,...

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PMID: 12697073
DOI: 10.1186/1471-2407-3-7

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