Article
Vitamin D receptor gene polymorphism in familial prostate cancer in a Japanese population.
International journal of urology : official journal of the Japanese Urological Association - 1 May 2003
Suzuki Kazuhiro, Matsui Hiroshi, Ohtake Nobuaki, Nakata Seiji, Takei Tomoyuki, Koike Hidekazu, Nakazato Haruki, Okugi Hironobu, Hasumi Masaru, Fukabori Yoshitatsu, Kurokawa Kohei, Yamanaka Hidetoshi
Abstract excerpt
AIM: Vitamin D acts as an antiproliferative agent against prostate cells. Epidemiological study has shown that a low level of serum vitamin D concentration is a risk factor for prostate cancer. Vitamin D acts via vitamin D receptor (VDR), and an association of genetic polymorphisms of the VDR gene has been reported. In the current study, we examined the association of VDR gene polymorphisms with familial prostate...
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