Article
[Tumor necrosis factor alpha HLA-DRB(1) gene polymorphism and genetic susceptibility to cirrhosis].
Zhonghua nei ke za zhi - 1 Dec 2002
Lin Jusheng, Cheng Yuanqiao, Tian Deying, Liao Jiazhi, Liu Nanzhi, Xiong Ping, Liang Kuohuan
Abstract excerpt
OBJECTIVE: To study the relationship between the gene polymorphism of HLA-DRB(1) and tumor necrosis factor (TNF)alpha with the genetic susceptibility to cirrhosis. METHODS: The gene polymorphism of DRB(1) and TNF alpha of 106 cases of cirrhosis due to HBV and 108 controls were detected by means of polymerase chain reaction-sequence specific primer and RFLP techniques. RESULTS: The frequency of DRB(1) * 120X and...
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