Article
Cellular phospholipid and cholesterol efflux in high-density lipoprotein deficiency.
Circulation - 18 Mar 2003
Marcil Michel, Bissonnette Rachel, Vincent Jérôme, Krimbou Larbi, Genest Jacques
Abstract excerpt
BACKGROUND: Prospective studies have examined the relationship between coronary artery disease and low plasma levels of high-density lipoprotein cholesterol (HDL-C). METHODS AND RESULTS: We investigated the causes of hypoalphalipoproteinemia (HypoA; HDL-C <5th percentile) in 64 subjects (12 women and 52 men). Apolipoprotein AI-mediated cellular cholesterol and phospholipid efflux were measured in fibroblasts from...
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