Article
Rheumatoid arthritis: proposal for the use of anti-microbial therapy in early cases.
Scandinavian journal of rheumatology - 1 Jan 2003
Ebringer Alan, Rashid Taha, Wilson Clyde
Abstract excerpt
Rheumatoid arthritis (RA) is a chronic disease, affecting women more than men, especially in those possessing the "shared epitope" (EQK/RRAA) amino acid sequences present in HLA-DR1/4 molecules. Proteus mirabilis carries sequences showing molecular mimicry to the "shared epitope" and to type XI collagen of hyaline cartilage. Elevated levels of antibodies to P. mirabilis have been reported from 14 different...
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