Article
The Fc gamma RIIIA-F158 allele is a risk factor for the development of lupus nephritis: a meta-analysis.
Kidney international - 1 Apr 2003
Karassa Fotini B, Trikalinos Thomas A, Ioannidis John P A
Abstract excerpt
BACKGROUND: The Fc gamma RIIIA-V/F158 polymorphism affects immunoglobulins (Ig)G1- and IgG3-binding capacity and may modulate the expression of renal disease in patients with systemic lupus erythematosus (SLE). We aimed to determine whether this polymorphism confers risk for the development of lupus nephritis and SLE in general. METHODS: A meta-analysis was performed based on the Medline and Embase databases...
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