Article
Remodeling of the Actin Cytoskeleton During Mammalian Sperm Capacitation and Acrosome Reaction1
1 Mar 2003
Abstract excerpt
The sperm acrosome reaction and penetration of the egg follow zona pellucida binding only if the sperm has previously undergone the poorly understood maturation process known as capacitation. We demonstrate here that in vitro capacitation of bull, ram, mouse, and human sperm was accompanied by a time-dependent increase in actin polymerization. Induction of the acrosome reaction in capacitated cells initiated fast...
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