Article
Assessment of Oocyte Quality Following Repeated Gonadotropin Stimulation in the Mouse1
1 Mar 2003
Abstract excerpt
The present study assessed the effects of repeated ovarian stimulation on oocyte quality. Female mice were stimulated with eCG and hCG at 1-wk intervals for 4 wk. Germinal vesicle (GV)-stage oocytes were evaluated in relation to size, somatic cell association, and chromatin organization after each week of stimulation. In addition, ATP content and expression of meiotic competence were monitored in GV and in vivo...
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