Article
Cre recombinase expression can result in phenotypic aberrations in plants.
Plant molecular biology - 1 Jan 2003
Coppoolse Eric R, de Vroomen Marianne J, Roelofs Dick, Smit Jaap, van Gennip Femke, Hersmus Bart J M, Nijkamp H John J, van Haaren Mark J J
Abstract excerpt
The cre recombinase gene was stably introduced and expressed in tomato, petunia and Nicotiana tabacum. Some plants expressing the cre gene driven by a CaMV 35S promoter displayed growth retardation and a distinct pattern of chlorosis in their leaves. Although no direct relation can be proven between the phenotype and cre expression, aberrant phenotypes always co-segregate with the transgene, which strongly...
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