Article
The Polycomb-group protein ENX-2 interacts with ZAP-70.
Immunology letters - 3 Mar 2003
Ogawa Motoyuki, Hiraoka Yoshiki, Aiso Sadakazu
Abstract excerpt
Human ENX-2 is a homologue of Drosophila Enhancer of zeste, which is a member of Polycomb-group proteins regulating the expression of homeotic genes as chromatin-associated proteins. In this study, we demonstrate that ENX-2 plays an important role as a signaling molecule involved in T cell receptor-mediated signaling pathway. In immunoprecipitation experiments, ENX-2 and zeta associated protein-70 (ZAP-70) were...
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