Article
CADASIL and genetics of cerebral ischaemia.
Journal of neural transmission. Supplementum - 1 Jan 2002
Kalaria R N, Low W C, Oakley A E, Slade J Y, Ince P G, Morris C M, Mizuno T
Abstract excerpt
Recent advances suggest the existence of several autosomal dominantly inherited forms of cerebrovascular disorders. Mutations in diverse genes may induce direct pathological changes in intracranial vessels to cause cerebral ischaemic or haemorrhagic strokes leading to cognitive impairment and dementia. Similar pathology may also be caused by systemic vascular disease resulting from mutations and polymorphisms in...
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