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Article

Impact of genetic manipulation on the fitness of Anopheles stephensi mosquitoes.

Science (New York, N.Y.) - 21 Feb 2003

Catteruccia Flaminia, Godfray H Charles J, Crisanti Andrea

Abstract excerpt

Genetic modification of mosquitoes offers exciting possibilities for controlling malaria, but success will depend on how transformation affects the fitness of modified insects. The expression of an exogenous gene, the mutations caused by its insertion, and inbreeding while transformed lines are established can all lead to reductions in fitness. Factors influencing fitness were investigated in cage experiments...

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Identifiers

PMID: 12595691
DOI: 10.1126/science.1081453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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