Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A family history of deoxyribonuclease II: surprises from Trichinella spiralis and Burkholderia pseudomallei.

Gene - 13 Feb 2003

MacLea Kyle S, Krieser Ronald J, Eastman Alan

Abstract excerpt

Deoxyribonuclease IIalpha (DNase IIalpha) is an acidic endonuclease found in lysosomes and nuclei, and it is also secreted. Though its Caenorhabditis elegans homolog, NUC-1, is required for digesting DNA of apoptotic cell corpses and dietary DNA, it is not required for viability. However, DNase IIalpha is required in mice for correct development and viability, because undigested cell corpses lead to lesions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Burkholderia pseudomallei
Share to Conserved Sequence
Share to Databases, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endodeoxyribonucleases

Share to Expressed Sequence Tags

Share to Fibroblasts

Share to Genome

Share to Histidine

Source

Identifiers

PMID: 12594037
DOI: 10.1016/s0378-1119(02)01233-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A family history of deoxyribonuclease II: surprises from Trichinella spiralis and Burkholderia pseudomallei.PMID 12594037Read ↗

Characterisation of a Plancitoxin-1-Like DNase II Gene in Trichinella spiralisSemantic proximity Read ↗

The draft genome of the parasitic nematode Trichinella spiralisSemantic proximity Read ↗

Molecular basis of differential parasitism between non-encapsulated and encapsulated <i>Trichinella</i> revealed by a high-quality genome assemblySemantic proximity Read ↗

Identification of stage-specifically expressed genes of<i>Trichinella spiralis</i>by suppression subtractive hybridizationSemantic proximity Read ↗

Comprehensive search for cysteine cathepsins in the human genomeSemantic proximity Read ↗

Ancient and current association of the <i>Trichinella</i> complex with negative-sense and double-stranded RNA virusesSemantic proximity Read ↗

Evolution of the RNA-dependent RNA polymerase (RdRP) genes: duplications and possible losses before and after the divergence of major eukaryotic groups.Semantic proximity Read ↗

Molecular identification of Trichinella spiralis nudix hydrolase and its induced protective immunity against trichinellosis in BALB/c miceSemantic proximity Read ↗

Comparative biochemical properties of vertebrate deoxyribonuclease I.Semantic proximity Read ↗

Identification of Differentially Expressed Genes of Trichinella spiralis Larvae after Exposure to Host Intestine MilieuSemantic proximity Read ↗

A superfamily of archaeal, bacterial, and eukaryotic proteins homologous to animal transglutaminasesSemantic proximity Read ↗

Transcription in the early diverging eukaryote Trichomonas vaginalis: an unusual RNA polymerase II and alpha-amanitin-resistant transcription of protein-coding genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.