Article
Genetic and biochemical characterization of the F-ATPase operon from Streptococcus sanguis 10904.
Journal of bacteriology - 1 Mar 2003
Kuhnert Wendi L, Quivey Robert G
Abstract excerpt
Oral streptococci utilize an F-ATPase to regulate cytoplasmic pH. Previous studies have shown that this enzyme is a principal determinant of aciduricity in the oral streptococcal species Streptococcus sanguis and Streptococcus mutans. Differences in the pH optima of the respective ATPases appears to be the main reason that S. mutans is more tolerant of low pH values than S. sanguis and hence pathogenic. We have...
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